Visual Predictions Operate on Different Timescales

Prediction at Different Timescales

Hysteresis in Processing of Perceptual Ambiguity on Three Different Timescales

Sensory information is a priori incomplete and ambiguous. Our perceptual system has to make predictions about the sources of the sensory information, based on concepts from perceptual memory in order to create stable and reliable percepts. We presented ambiguous and disambiguated lattice stimuli (variants of the Necker cube) in order to measure a hysteresis effects in visual perception. Fifteen...

Cerebellar modules operate at different frequencies

Due to the uniform cyto-architecture of the cerebellar cortex, its overall physiological characteristics have traditionally been considered to be homogeneous. In this study, we show in awake mice at rest that spiking activity of Purkinje cells, the sole output cells of the cerebellar cortex, differs between cerebellar modules and correlates with their expression of the glycolytic enzyme aldolas...

Timescales of Inference in Visual Adaptation

Adaptation is a hallmark of sensory function. Adapting optimally requires matching the dynamics of adaptation to those of changes in the stimulus distribution. Here we show that the dynamics of adaptation in the responses of mouse retinal ganglion cells depend on stimulus history. We hypothesized that the accumulation of evidence for a change in the stimulus distribution controls the dynamics o...

Hierarchical decision processes that operate over distinct timescales underlie choice and changes in strategy.

Decision-making in a natural environment depends on a hierarchy of interacting decision processes. A high-level strategy guides ongoing choices, and the outcomes of those choices determine whether or not the strategy should change. When the right decision strategy is uncertain, as in most natural settings, feedback becomes ambiguous because negative outcomes may be due to limited information or...